# HISTORY
25 Mar 2016: Updated by: TOUCHUP-v1.15
15 Mar 2016: Updated by: TOUCHUP-v1.14

# molecular_function
20140604: Eukaryota_PTN000315667 contributes to function Atg8 ligase activity (GO:0019776) 

# cellular_component
20140604: Eukaryota_PTN000315667 is found in pre-autophagosomal structure membrane (GO:0034045) 
20140604: Eukaryota_PTN000315667 is found in Atg12-Atg5-Atg16 complex (GO:0034274) 

# biological_process
20140604: Eukaryota_PTN000315667 participates in C-terminal protein lipidation (GO:0006501) 
20140611: Eukaryota_PTN000315667 participates in nucleophagy (GO:0044804) 
20140604: Eukaryota_PTN000315667 participates in mitophagy (GO:0000422) 
20140604: Eukaryota_PTN000315667 participates in autophagosome assembly (GO:0000045) 
20140611: Eukaryota_PTN000315667 participates in cellular response to nitrogen starvation (GO:0006995) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES
CC: It is not clear whether ATG5 is still present in mature autophagic vesicles.
MAF 2014-06-11
Reviewed with PG

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).