# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 15 Mar 2016: Updated by: TOUCHUP-v1.14 25 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20151023: Eukaryota_PTN000313393 has function nucleocytoplasmic transporter activity (GO:0005487) 20151023: Eukaryota_PTN000313393 has function structural constituent of nuclear pore (GO:0017056) # cellular_component 20151023: Eukaryota_PTN000313393 is found in nuclear pore central transport channel (GO:0044613) # biological_process 20151023: Eukaryota_PTN000313393 participates in NLS-bearing protein import into nucleus (GO:0006607) 20151023: Eukaryota_PTN000313393 participates in protein targeting to nuclear inner membrane (GO:0036228) 20151023: Eukaryota_PTN000313393 participates in nuclear pore organization (GO:0006999) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES This family comprises the NUP54 (aka Nup57 in S. cerevisiae) subunit of the nuclear pore complex. It is part of the Nup62 subcomplex (Kabachinski & Schwartz 2015; PMID:26046137). # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).