# HISTORY 25 Mar 2016: Updated by: TOUCHUP-v1.15 15 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20151014: Eukaryota_PTN000308454 has function 3'-5' DNA helicase activity (GO:0043138) # cellular_component 20151014: Eukaryota_PTN000308454 is found in GINS complex (GO:0000811) # biological_process 20151014: Eukaryota_PTN000308454 participates in DNA strand elongation involved in mitotic DNA replication (GO:1902983) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES Revieed in PMID:22329974 and PMID:23412083 Missing primary annotations to GO:0006268 DNA unwinding involved in DNA replication. # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).