# HISTORY
25 Mar 2016: Updated by: TOUCHUP-v1.15
15 Mar 2016: Updated by: TOUCHUP-v1.14

# molecular_function
20140604: Eukaryota_PTN000305308 has function Atg8 ligase activity (GO:0019776) 

# cellular_component
20140604: Eukaryota_PTN000305308 is found in cytoplasmic ubiquitin ligase complex (GO:0000153) 
20140604: Eukaryota_PTN000305308 is found in cytosol (GO:0005829) 

# biological_process
20140611: Eukaryota_PTN000305308 participates in nucleophagy (GO:0044804) 
20140604: Eukaryota_PTN000305308 participates in autophagosome assembly (GO:0000045) 
20140611: Eukaryota_PTN000305308 participates in mitophagy (GO:0000422) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES
ATG3 is a E2 enzyme that transfers the ATG8 ubiquitin-like onto phosphatidyl ethanolamine (PE), thus, it's a lipid modifier, not a protein modifier.
There is evidence in mouse that ATG3 is a substrate for ATG12 conjugation (PMID:20723759), which would also implicate ATG3 as a 'protein modifer'. But the evidence in yeast shows that ATG3 is a 'lipid modifer', acting on PE.
MAF 2014-06-11
Reviewed with PG

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).