# HISTORY
04 Aug 2016: Updated by: TOUCHUP-v1.21

# molecular_function
20160428: root_PTN000302827 has function methyltransferase activity (GO:0008168) 
20160428: Eukaryota_PTN000302828 has function mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity (GO:0016422) 
20160428: Eukaryota_PTN000375324 has function site-specific DNA-methyltransferase (adenine-specific) activity (GO:0009007) 
20160428: Schizosaccharomyces pombe_SPAC22G7.07c has LOST/MODIFIED function site-specific DNA-methyltransferase (adenine-specific) activity (GO:0009007) 

# cellular_component
20160428: root_PTN000302827 is found in nucleus (GO:0005634) 
20160428: Eukaryota_PTN000302828 is found in nuclear speck (GO:0016607) 
20160428: Eukaryota_PTN000302828 is found in MIS complex (GO:0036396) 

# biological_process
20160428: Eukaryota_PTN000302828 participates in RNA methylation (GO:0001510) 
20160428: Eumetazoa_PTN000981980 participates in mRNA splicing, via spliceosome (GO:0000398) 
20160428: Eumetazoa_PTN000981980 participates in primary miRNA methylation (GO:1990744) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).