# HISTORY 25 Mar 2016: Updated by: TOUCHUP-v1.15 15 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20150814: Metazoa_PTN001759454 has function gamma-catenin binding (GO:0045295) 20150813: Metazoa_PTN001759454 has function beta-catenin binding (GO:0008013) # cellular_component 20150813: Metazoa_PTN001759454 is found in beta-catenin destruction complex (GO:0030877) 20150814: Metazoa_PTN001759454 co-localizes with cytoplasmic microtubule (GO:0005881) # biological_process 20150814: Metazoa_PTN001759454 participates in cell proliferation (GO:0008283) 20150814: Metazoa_PTN001759454 participates in regulation of cell differentiation (GO:0045595) 20150814: Metazoa_PTN001759454 participates in cell migration (GO:0016477) 20150814: Metazoa_PTN001759454 participates in negative regulation of microtubule depolymerization (GO:0007026) 20150814: Metazoa_PTN001759454 participates in positive regulation of protein catabolic process (GO:0045732) 20150814: Metazoa_PTN001759454 participates in cell fate specification (GO:0001708) 20150814: Metazoa_PTN001759454 participates in pattern specification process (GO:0007389) 20150814: Metazoa_PTN001759454 participates in negative regulation of canonical Wnt signaling pathway (GO:0090090) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).