# HISTORY 23 May 2016: Saved by pascalegaudet using Paint 2.0-beta19 15 Mar 2016: Updated by: TOUCHUP-v1.14 25 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20150408: root_PTN000286163 has function mRNA 3'-UTR binding (GO:0003730) 20150408: root_PTN000286163 has function translation factor activity, RNA binding (GO:0008135) 20150408: root_PTN000286163 has function ribosome binding (GO:0043022) 20150408: root_PTN000286163 has function translation repressor activity, nucleic acid binding (GO:0000900) # cellular_component 20150408: root_PTN000286163 is found in neuron projection (GO:0043005) 20150408: root_PTN000286163 is found in messenger ribonucleoprotein complex (GO:1990124) 20150408: root_PTN000286163 is found in synapse (GO:0045202) 20150408: root_PTN000286163 is found in cytoplasm (GO:0005737) 20150408: root_PTN000286163 is found in nucleus (GO:0005634) 20150408: Caenorhabditis elegans_PTN001758165 is NOT found in synapse (GO:0045202) 20150408: Caenorhabditis elegans_PTN001758165 is NOT found in neuron projection (GO:0043005) # biological_process 20150408: root_PTN000286163 participates in negative regulation of cytoplasmic translation (GO:2000766) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES Removed annotations to synapse (GO:0045202) and neuron projection (GO:0043005) based on dispute from K. VanAuken (Jira GO-1085). PG 2016-05-23 # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).