# HISTORY 04 Aug 2016: Updated by: TOUCHUP-v1.21 # molecular_function 20160502: Eukaryota_PTN000281946 has function Rab guanyl-nucleotide exchange factor activity (GO:0017112) 20160502: Eukaryota_PTN000281946 has function Rab GTPase binding (GO:0017137) # cellular_component 20160502: Eukaryota_PTN000281946 is found in RIC1-RGP1 guanyl-nucleotide exchange factor complex (GO:0034066) 20160502: Eukaryota_PTN000281946 is found in Golgi membrane (GO:0000139) # biological_process 20160502: Eukaryota_PTN000281946 participates in retrograde transport, endosome to Golgi (GO:0042147) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).