# HISTORY 24 Jan 2017: Saved by krc using Paint v2.29 on 24 Jan 2017 using PANTHER version UPL 11.0 # molecular_function 20170124: root_PTN000277823 contributes to function ATP-dependent microtubule motor activity, plus-end-directed (GO:0008574) 20170124: root_PTN000277823 has function dynein heavy chain binding (GO:0045504) 20170124: root_PTN000277823 has function dynein light chain binding (GO:0045503) # cellular_component 20170124: root_PTN000277823 is found in dynein complex (GO:0030286) 20170124: Eukaryota_PTN000277824 is found in cytoplasmic dynein complex (GO:0005868) 20170124: Eukaryota_PTN000278083 is found in cytoplasmic dynein complex (GO:0005868) 20170124: Eukaryota_PTN000278083 is found in ciliary plasm (GO:0097014) 20170124: Eukaryota_PTN000277911 is found in axonemal dynein complex (GO:0005858) 20170124: Eukaryota_PTN000278033 is found in outer dynein arm (GO:0036157) 20170124: Eukaryota_PTN000966144 is found in cilium (GO:0005929) 20170124: Candida albicans SC5314_CAL0000862 is NOT found in outer dynein arm (GO:0036157) 20170124: Eukaryota_PTN000277955 is found in outer dynein arm (GO:0036157) # biological_process 20170124: Eukaryota_PTN000277824 participates in transport along microtubule (GO:0010970) 20170124: Eukaryota_PTN000277824 participates in transport along microtubule (GO:0010970) 20170124: Eukaryota_PTN000277824 participates in positive regulation of ATP-dependent microtubule motor activity, plus-end-directed (GO:2000582) 20170124: Eukaryota_PTN000278083 participates in intraciliary transport (GO:0042073) 20170124: Eukaryota_PTN000277911 participates in cilium movement (GO:0003341) 20170124: Eukaryota_PTN000278033 participates in outer dynein arm assembly (GO:0036158) 20170124: Eukaryota_PTN000278033 participates in cilium movement (GO:0003341) 20170124: Eukaryota_PTN000277955 participates in cilium movement (GO:0003341) 20170124: Candida albicans SC5314_CAL0000862 does NOT participate in outer dynein arm assembly (GO:0036158) 20170124: Eukaryota_PTN000277955 participates in outer dynein arm assembly (GO:0036158) 20170124: root_PTN000277823 participates in microtubule-based movement (GO:0007018) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES This is a family of dynein intermediate chains, some axonemal and some cytoplasmic. Some clades have enough experimental evidence to get to function known from sequence analysis, but a few do not. 9ZZZZ:PTN000277823 - 9EUKA:PTN000277992: WDR63 & Cr IDA7 (no EXP; have entered annots for IDA7) - 9EUKA:PTN000277824 -- 9EUKA:PTN000277825 --- PTN000277826 ---- PTN000966099 ----- 9BILA:PTN000277827 ------ PTN001752814 ------- 9ZZZZ:PTN000277830 -------- 9EUTE:PTN000277854: DYNC1I2 -------- 9EUTE:PTN000277831: DYNC1I1 ------ PTN000277888: insect seqs incl: Dmel sw ---- 9FUNG:PTN000966122: Sc PAC11 (dynein intermediate chain) --- PTN000966137: Dicty incl: dlcA (cytoplasmic dynein intermediate chain) - 9EUKA:PTN000278083: WDR34 & Cr FAP133 (not much EXP) - 9EUKA:PTN000277911: WDR78, Dmel Dlc61B, & Cr BOP5 - 9EUKA:PTN000278033: DNAI2 & Cr ODA6 - 9EUKA:PTN000966144: WDR60 & Cr FAP163 - 9EUKA:PTN000277955: DNAI1 (dynein intermediate chain, axonemal) & Cr ODA9 # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).