# HISTORY
23 May 2016: Saved by pascalegaudet using Paint 2.0-beta15

# molecular_function

# cellular_component

# biological_process
20091110: Homo sapiens_16930 to cellular calcium ion homeostasis (GO:0006874)  was challenged because Annotations seems out of date; see PMID 23148228 which claims that "CHERP acts in the nucleus to impact cellular proliferation by regulating the function of the U2 snRNA spliceosomal complex. The previously reported effects of CHERP on cellular growth therefore are likely indirect effects of altered spliceosomal function, consistent with prior data showing that loss of function of U2 snRNP components can interfere with cell growth and induce cell cycle arrest."
Do not annotate. PG 2016-05-23
# CHALLENGED

23 May 2016: Homo sapiens_16930 annotation to cellular calcium ion homeostasis (GO:0006874) from [PMID:10794731] was challenged

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).