# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 15 Mar 2016: Updated by: TOUCHUP-v1.14 25 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20150316: Eukaryota_PTN000267771 has function RNA binding (GO:0003723) # cellular_component 20150316: Eukaryota_PTN000267771 is found in nucleolus (GO:0005730) # biological_process 20150316: Eukaryota_PTN000267771 participates in endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (GO:0000480) 20150316: Eukaryota_PTN000267771 participates in small-subunit processome assembly (GO:0034462) 20150316: Eukaryota_PTN000267771 participates in endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (GO:0000447) 20150316: Eukaryota_PTN000267771 participates in endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (GO:0000472) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES MAF: Very different functions between human and yeast. However, the function discribed in yeast by PMID:15964808 seem more relevant with experimental data. # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).