# HISTORY 25 Mar 2016: Updated by: TOUCHUP-v1.15 15 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20150529: root_PTN000258330 has function glucosyltransferase activity (GO:0046527) 20150528: Eumetazoa_PTN000954275 has function UDP-xylosyltransferase activity (GO:0035252) 20150528: Eumetazoa_PTN000954275 has function UDP-glucosyltransferase activity (GO:0035251) # cellular_component 20150529: node_PTN000258331 is found in endomembrane system (GO:0012505) 20150529: node_PTN000258341 is found in endoplasmic reticulum lumen (GO:0005788) # biological_process 20150529: root_PTN000258330 participates in glycolipid metabolic process (GO:0006664) 20150528: Bilateria_PTN000258397 participates in positive regulation of Notch signaling pathway (GO:0045747) 20150528: Bilateria_PTN000258397 participates in protein O-linked glycosylation (GO:0006493) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).