# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 15 Mar 2016: Updated by: TOUCHUP-v1.14 25 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20151030: Eukaryota_PTN000953562 has function zinc ion transmembrane transporter activity (GO:0005385) # cellular_component 20151030: Eukaryota_PTN000953562 is found in integral component of plasma membrane (GO:0005887) # biological_process 20151030: Eukaryota_PTN000953562 participates in cellular zinc ion homeostasis (GO:0006882) 20151030: Eukaryota_PTN000953562 participates in zinc II ion transmembrane import (GO:0071578) 20151030: Tetrapoda_PTN000257280 participates in BMP signaling pathway (GO:0030509) 20151030: Tetrapoda_PTN000257387 participates in positive regulation of B cell receptor signaling pathway (GO:0050861) 20151030: Euteleostomi_PTN000257363 participates in signal transduction (GO:0007165) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).