# HISTORY 25 Mar 2016: Updated by: TOUCHUP-v1.15 15 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20141115: Eukaryota_PTN000256564 has function phosphatidate phosphatase activity (GO:0008195) 20141121: Eukaryota_PTN000256565 has function transcription coactivator activity (GO:0003713) # cellular_component 20141121: Eukaryota_PTN000256565 is found in nucleus (GO:0005634) 20141121: Euteleostomi_PTN000256598 is found in endoplasmic reticulum membrane (GO:0005789) 20141121: Euteleostomi_PTN000256598 is found in cytosol (GO:0005829) 20141121: Euteleostomi_PTN000256571 is found in mitochondrial outer membrane (GO:0005741) # biological_process 20141121: Eukaryota_PTN000256565 participates in positive regulation of transcription from RNA polymerase II promoter (GO:0045944) 20141120: Eukaryota_PTN000256565 participates in fatty acid catabolic process (GO:0009062) 20141120: Eukaryota_PTN000256565 participates in triglyceride biosynthetic process (GO:0019432) # PRUNED 25 Mar 2016: Eukaryota_PTN000953228 has been pruned from tree # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES 15 Mar 2016: Eukaryota_PTN000953228 has been pruned from tree # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).