# HISTORY
25 Mar 2016: Updated by: TOUCHUP-v1.15
15 Mar 2016: Updated by: TOUCHUP-v1.14

# molecular_function
20151030: root_PTN001742129 has function aspartic endopeptidase activity, intramembrane cleaving (GO:0042500) 

# cellular_component
20151030: node_PTN000256093 is found in integral component of lumenal side of endoplasmic reticulum membrane (GO:0071556) 
20151030: node_PTN000256093 is found in integral component of cytoplasmic side of endoplasmic reticulum membrane (GO:0071458) 
20151030: node_PTN000256093 is found in Golgi-associated vesicle membrane (GO:0030660) 
20151030: node_PTN000256093 is found in lysosomal membrane (GO:0005765) 

# biological_process
20151030: root_PTN001742129 participates in membrane protein proteolysis (GO:0033619) 
20151030: root_PTN001742129 participates in signal peptide processing (GO:0006465) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).