# HISTORY
25 Mar 2016: Updated by: TOUCHUP-v1.15
15 Mar 2016: Updated by: TOUCHUP-v1.14

# molecular_function
20151117: Eukaryota_PTN000249931 has function nucleocytoplasmic transporter activity (GO:0005487) 
20151117: Eukaryota_PTN000249931 has function structural constituent of nuclear pore (GO:0017056) 
20151117: Eukaryota_PTN000249931 has function phospholipid binding (GO:0005543) 

# cellular_component
20151117: Eukaryota_PTN000249931 is found in nuclear pore central transport channel (GO:0044613) 

# biological_process
20151117: Eukaryota_PTN000249931 participates in RNA export from nucleus (GO:0006405) 
20151117: Eukaryota_PTN000249931 participates in ribonucleoprotein complex export from nucleus (GO:0071426) 
20151117: Eukaryota_PTN000249931 participates in protein import into nucleus (GO:0006606) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES
This family contains the NUP62 (aka NSP1 in S cerevisiae) family of nuclear pore components. It is specifically part of the central channel [Hoelz et al. 2011 (PMID:21495847), Aitchison and Rout 2012 (PMID:22419078), and Kabachinski and Schwartz 2015 (PMID:26046137).
In vertebrates, there is a duplicated gene NUP62CL. In rat, mouse, and human, this gene contains the most conserved core portion of the C-terminus but has large duplications of the N-terminus and a smaller section of the end of the C-terminus. However the other vertebrate sequences do not appear to have lost these sections of the sequence.

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).