# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 15 Mar 2016: Updated by: TOUCHUP-v1.14 25 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20150703: Euteleostomi_PTN000948235 has function microtubule binding (GO:0008017) # cellular_component 20150703: Euteleostomi_PTN000948235 is found in mitochondrion (GO:0005739) 20150703: Theria _PTN000948237 is found in immunological synapse (GO:0001772) # biological_process 20150703: Deuterostomia_PTN001738899 participates in meiosis I (GO:0007127) 20150703: Euteleostomi_PTN000948235 participates in positive regulation of apoptotic process (GO:0043065) 20150703: Euteleostomi_PTN000948235 does NOT participate in meiosis I (GO:0007127) 20150703: Theria _PTN000948237 does NOT participate in meiosis I (GO:0007127) 20150703: node_PTN000948251 does NOT participate in meiosis I (GO:0007127) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).