# HISTORY 25 Mar 2016: Updated by: TOUCHUP-v1.15 15 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20150819: root_PTN000247701 has function nicotinamide-nucleotide adenylyltransferase activity (GO:0000309) 20150819: root_PTN000247701 has function nicotinate-nucleotide adenylyltransferase activity (GO:0004515) # cellular_component 20150819: Fungi_PTN000948002 is found in nucleus (GO:0005634) 20150819: Euteleostomi_PTN000247709 is found in Golgi apparatus (GO:0005794) 20150819: Euteleostomi_PTN000247753 is found in nucleus (GO:0005634) 20150819: Chordata_PTN001738739 is found in mitochondrion (GO:0005739) # biological_process 20150819: root_PTN000247701 participates in 'de novo' NAD biosynthetic process from aspartate (GO:0034628) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).