# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 15 Mar 2016: Updated by: TOUCHUP-v1.14 25 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20150615: root_PTN000241033 has function identical protein binding (GO:0042802) 20150615: root_PTN000241033 has function pyridoxal phosphate binding (GO:0030170) 20150612: node_PTN001736404 has function N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity (GO:0003992) 20150612: Bacteria _PTN000241477 has function butane-1,4-diamine:2-oxoglutarate aminotransferase activity (GO:0033094) 20150612: node_PTN000944876 has function 4-aminobutyrate transaminase activity (GO:0003867) 20150615: node_PTN000241343 has function adenosylmethionine-8-amino-7-oxononanoate transaminase activity (GO:0004015) 20150615: Eukaryota_PTN000241344 has function dethiobiotin synthase activity (GO:0004141) 20150617: Eukaryota_PTN000241036 has function alanine-glyoxylate transaminase activity (GO:0008453) 20150615: node_PTN000241154 has function ornithine-oxo-acid transaminase activity (GO:0004587) 20150612: Bacteria _PTN000241312 has LOST/MODIFIED function 4-aminobutyrate transaminase activity (GO:0003867) 20150615: node_PTN000944939 has LOST/MODIFIED function dethiobiotin synthase activity (GO:0004141) 20150612: Bacteria _PTN000241477 has LOST/MODIFIED function N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity (GO:0003992) # cellular_component 20150612: node_PTN001736404 is found in cytosol (GO:0005829) 20150612: Eukaryota_PTN000241284 is found in mitochondrial matrix (GO:0005759) 20150612: Viridiplantae_PTN000241297 is found in chloroplast stroma (GO:0009570) 20150612: Eukaryota_PTN000241230 is found in mitochondrion (GO:0005739) 20150615: Eukaryota_PTN000241344 is found in mitochondrion (GO:0005739) 20150617: Eukaryota_PTN000241036 is found in mitochondrion (GO:0005739) 20150615: Embryophyta_PTN000944856 is found in chloroplast (GO:0009507) 20150615: node_PTN000241154 is found in cytoplasm (GO:0005737) 20150612: Saccharomyces cerevisiae S288c_S000003251 is NOT found in mitochondrion (GO:0005739) # biological_process 20150612: node_PTN001736404 participates in arginine biosynthetic process (GO:0006526) 20150612: Bacteria _PTN000241477 participates in putrescine catabolic process (GO:0009447) 20150612: Enterobacteriaceae_PTN001736444 participates in arginine catabolic process (GO:0006527) 20150615: node_PTN000944876 participates in gamma-aminobutyric acid catabolic process (GO:0009450) 20150615: node_PTN000241343 participates in biotin biosynthetic process (GO:0009102) 20150618: Mammalia_PTN000241043 participates in glyoxylate catabolic process (GO:0009436) 20150618: Mammalia_PTN000241043 participates in positive regulation of nitric oxide biosynthetic process (GO:0045429) 20150618: Mammalia_PTN000241043 participates in L-alanine catabolic process, by transamination (GO:0019481) 20150615: node_PTN000241365 participates in porphyrin-containing compound biosynthetic process (GO:0006779) 20150615: node_PTN000241154 participates in arginine catabolic process to glutamate (GO:0019544) 20150615: node_PTN000241154 participates in arginine catabolic process to proline via ornithine (GO:0010121) 20150612: Enterobacteriaceae_PTN001736444 does NOT participate in arginine biosynthetic process (GO:0006526) 20150615: Bacteria _PTN000241312 does NOT participate in gamma-aminobutyric acid catabolic process (GO:0009450) 20150612: Bacteria _PTN000241477 does NOT participate in arginine biosynthetic process (GO:0006526) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).