# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 15 Mar 2016: Updated by: TOUCHUP-v1.14 25 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20150506: root_PTN000231842 has function 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity (GO:0046538) 20150506: Saccharomycetaceae_PTN000231955 has LOST/MODIFIED function 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity (GO:0046538) # cellular_component 20150506: root_PTN000231842 is found in cytosol (GO:0005829) # biological_process 20150506: root_PTN000231842 participates in glycolytic process (GO:0006096) 20150506: root_PTN000231842 participates in gluconeogenesis (GO:0006094) 20150506: root_PTN000231842 participates in regulation of pentose-phosphate shunt (GO:0043456) 20150506: Saccharomycetaceae_PTN000231955 does NOT participate in glycolytic process (GO:0006096) 20150506: Saccharomycetaceae_PTN000231955 does NOT participate in gluconeogenesis (GO:0006094) 20150506: Saccharomycetaceae_PTN000231955 does NOT participate in regulation of pentose-phosphate shunt (GO:0043456) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).