# HISTORY 25 Mar 2016: Updated by: TOUCHUP-v1.15 15 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20160301: root_PTN000229986 has function catalytic activity (GO:0003824) 20160301: Embryophyta_PTN000938564 has function peptidase activity (GO:0008233) 20160301: node_PTN000229987 has function GMP synthase activity (GO:0003921) 20160301: node_PTN000229987 has function GMP synthase (glutamine-hydrolyzing) activity (GO:0003922) 20160301: node_PTN000230192 has function hydrolase activity (GO:0016787) 20160301: Bacteria _PTN000230196 has function gamma-glutamyl-gamma-aminobutyrate hydrolase activity (GO:0033969) 20160301: node_PTN000230074 has function anthranilate synthase activity (GO:0004049) 20160301: Bacilli_PTN001729054 has function 4-amino-4-deoxychorismate synthase activity (GO:0046820) 20160301: Gammaproteobacteria_PTN000230115 has function anthranilate phosphoribosyltransferase activity (GO:0004048) 20160301: Gammaproteobacteria_PTN000747575 has function 4-amino-4-deoxychorismate synthase activity (GO:0046820) # cellular_component 20160301: root_PTN000229986 is found in cytosol (GO:0005829) 20160301: node_PTN000230074 is found in anthranilate synthase complex (GO:0005950) # biological_process 20160301: Embryophyta_PTN000938564 participates in glucosinolate metabolic process (GO:0019760) 20160301: node_PTN000229987 participates in GMP biosynthetic process (GO:0006177) 20160301: node_PTN000230153 participates in tryptophan biosynthetic process (GO:0000162) 20160301: Bacteria _PTN000230196 participates in polyamine catabolic process (GO:0006598) 20160301: node_PTN000230074 participates in tryptophan biosynthetic process (GO:0000162) 20160301: Bacilli_PTN001729054 participates in tetrahydrofolate biosynthetic process (GO:0046654) 20160301: Gammaproteobacteria_PTN000230115 participates in phenazine biosynthetic process (GO:0002047) 20160301: Gammaproteobacteria_PTN000747575 participates in tetrahydrofolate biosynthetic process (GO:0046654) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).