# HISTORY
25 Mar 2016: Updated by: TOUCHUP-v1.15
15 Mar 2016: Updated by: TOUCHUP-v1.14

# molecular_function
20150807: Eukaryota_PTN000221451 has function RNA binding (GO:0003723) 

# cellular_component
20150807: Eukaryota_PTN000221451 is found in U2-type prespliceosome (GO:0071004) 
20150807: Eukaryota_PTN000221451 is found in U1 snRNP (GO:0005685) 

# biological_process
20150807: Eukaryota_PTN000221451 participates in mRNA splicing, via spliceosome (GO:0000398) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES
This family contains the PRP40 subunit of the U1 snRNP.
The U1 snRNP is one the first snRNP to assemble onto the pre-mRNA, recognizing the 5' splice site   (Wahl et al. 2009 PMID:19239890).

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).