# HISTORY 24 Mar 2016: Updated by: TOUCHUP-v1.15 14 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20150820: root_PTN000206904 has function tRNA binding (GO:0000049) 20150820: node_PTN000206950 has function alanine-tRNA ligase activity (GO:0004813) 20150820: node_PTN000206950 has function amino acid binding (GO:0016597) 20150820: node_PTN000206905 has function Ser-tRNA(Ala) hydrolase activity (GO:0002196) # cellular_component 20150820: Viridiplantae_PTN000207029 is found in mitochondrion (GO:0005739) 20150820: Viridiplantae_PTN000207029 is found in cytosol (GO:0005829) 20150820: Viridiplantae_PTN000207029 is found in chloroplast (GO:0009507) 20150820: Bacteria _PTN000207063 is found in cytosol (GO:0005829) 20150820: Viridiplantae_PTN000207051 is found in mitochondrion (GO:0005739) 20150820: Viridiplantae_PTN000207051 is found in chloroplast (GO:0009507) 20150820: Opisthokonta_PTN000206955 is found in mitochondrion (GO:0005739) 20150820: Bilateria_PTN000925680 is NOT found in cytosol (GO:0005829) 20150820: Fungi_PTN000925648 is NOT found in cytosol (GO:0005829) 20150820: Bilateria_PTN000206956 is NOT found in mitochondrion (GO:0005739) 20150820: Viridiplantae_PTN000207051 is NOT found in cytosol (GO:0005829) # biological_process 20150820: node_PTN000206950 participates in tRNA modification (GO:0006400) 20150820: node_PTN000206950 participates in alanyl-tRNA aminoacylation (GO:0006419) 20150820: Bilateria_PTN000925680 participates in mitochondrial alanyl-tRNA aminoacylation (GO:0070143) 20150820: node_PTN000206905 participates in regulation of translational fidelity (GO:0006450) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).