# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 24 Mar 2016: Updated by: TOUCHUP-v1.15 14 Mar 2016: Updated by: TOUCHUP-v1.14 07 May 2016: Updated by: TOUCHUP-v1.18 # molecular_function 20150819: root_PTN001717497 contributes to function prenyltransferase activity (GO:0004659) 20150819: Eukaryota_PTN000206624 contributes to function protein farnesyltransferase activity (GO:0004660) 20150819: Eukaryota_PTN000206684 contributes to function CAAX-protein geranylgeranyltransferase activity (GO:0004662) 20150819: Eukaryota_PTN000206738 contributes to function Rab geranylgeranyltransferase activity (GO:0004663) # cellular_component 20150819: Eukaryota_PTN000206624 is found in protein farnesyltransferase complex (GO:0005965) 20150819: Eukaryota_PTN000206684 is found in CAAX-protein geranylgeranyltransferase complex (GO:0005953) 20150819: Eukaryota_PTN000206738 is found in Rab-protein geranylgeranyltransferase complex (GO:0005968) # biological_process 20150819: root_PTN001717497 participates in protein prenylation (GO:0018342) 20150819: Eukaryota_PTN000206624 participates in protein farnesylation (GO:0018343) 20150819: Eukaryota_PTN000206684 participates in protein geranylgeranylation (GO:0018344) 20150819: Eukaryota_PTN000206738 participates in protein geranylgeranylation (GO:0018344) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).