# HISTORY 24 Mar 2016: Updated by: TOUCHUP-v1.15 14 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function # cellular_component 20141212: root_PTN000200094 is found in EKC/KEOPS complex (GO:0000408) 20141212: Actinomycetales_PTN000921584 is NOT found in EKC/KEOPS complex (GO:0000408) 20141212: Cyanobacteria_PTN000921586 is NOT found in EKC/KEOPS complex (GO:0000408) 20141212: Bacteria _PTN000200224 is NOT found in EKC/KEOPS complex (GO:0000408) 20141212: Bacillus subtilis subsp. subtilis str. 168_BSU05940 is NOT found in EKC/KEOPS complex (GO:0000408) # biological_process 20141212: root_PTN000200094 participates in tRNA threonylcarbamoyladenosine modification (GO:0002949) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES MAF: Keops is conserved in archea and eukaryotes. # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).