# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 14 Mar 2016: Updated by: TOUCHUP-v1.14 24 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20151112: root_PTN000192346 has function DNA binding (GO:0003677) 20151112: root_PTN000192346 has function RNA polymerase II transcription factor activity, sequence-specific DNA binding (GO:0000981) # cellular_component 20151112: root_PTN000192346 is found in nucleoplasm (GO:0005654) 20151112: root_PTN000192346 is found in cytoplasm (GO:0005737) # biological_process 20151112: Chordata_PTN001364370 participates in multicellular organism development (GO:0007275) 20151112: Chordata_PTN001364370 participates in regulation of cell morphogenesis (GO:0022604) 20151112: Chordata_PTN001364370 participates in cytoskeleton organization (GO:0007010) 20151112: Eukaryota_PTN001708651 participates in multicellular organism development (GO:0007275) 20151112: Euteleostomi_PTN000915892 participates in positive regulation of glycogen (starch) synthase activity (GO:2000467) 20151112: Euteleostomi_PTN000915892 participates in response to insulin (GO:0032868) 20151112: Euteleostomi_PTN000915892 participates in positive regulation of glycogen biosynthetic process (GO:0045725) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).