# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 14 Mar 2016: Updated by: TOUCHUP-v1.14 24 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20150819: root_PTN000176640 has function phosphoribosylaminoimidazole carboxylase activity (GO:0004638) 20150819: root_PTN000176640 has function phosphoribosylaminoimidazolesuccinocarboxamide synthase activity (GO:0004639) # cellular_component 20150819: Bacteria _PTN000549225 is found in cytosol (GO:0005829) 20150819: Eukaryota_PTN000176703 is found in chloroplast stroma (GO:0009570) 20150819: node_PTN000176641 is found in cytosol (GO:0005829) 20150819: node_PTN000549240 is found in cytosol (GO:0005829) # biological_process 20150819: root_PTN000176640 participates in 'de novo' IMP biosynthetic process (GO:0006189) 20150819: root_PTN000176640 participates in adenine biosynthetic process (GO:0046084) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).