# HISTORY 24 Mar 2016: Updated by: TOUCHUP-v1.15 14 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20160127: root_PTN000171662 has function acrosin binding (GO:0032190) # cellular_component 20160128: root_PTN000171662 is found in extracellular matrix (GO:0031012) # biological_process 20160128: root_PTN000171662 participates in binding of sperm to zona pellucida (GO:0007339) 20160128: root_PTN000171662 participates in positive regulation of acrosome reaction (GO:2000344) 20160128: root_PTN000171662 participates in egg coat formation (GO:0035803) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES This family contains the ZP3 zona pellucida glycoprotein which is part of the specialized extracellular matrix of the oocyte and required for the acrosome reaction of the sperm cell. # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).