# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 14 Mar 2016: Updated by: TOUCHUP-v1.14 24 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20150313: cellular organisms_PTN000168373 has function thermospermine synthase activity (GO:0010487) 20150313: Fungi_PTN000900719 has function transferase activity, transferring alkyl or aryl (other than methyl) groups (GO:0016765) 20150313: Opisthokonta_PTN000900684 has function spermine synthase activity (GO:0016768) 20150313: Opisthokonta_PTN000900703 has function spermidine synthase activity (GO:0004766) 20150313: Embryophyta_PTN000900746 has function spermidine synthase activity (GO:0004766) 20150313: Bacteria _PTN000168362 has function spermidine synthase activity (GO:0004766) # cellular_component 20150313: Eukaryota_PTN000900648 is found in cytoplasm (GO:0005737) 20150313: Bacteria _PTN000168362 is found in cytosol (GO:0005829) # biological_process 20150313: node_PTN000168372 participates in polyamine biosynthetic process (GO:0006596) 20150313: cellular organisms_PTN000900683 participates in polyamine biosynthetic process (GO:0006596) 20150313: Opisthokonta_PTN000900684 participates in spermine biosynthetic process (GO:0006597) 20150313: Opisthokonta_PTN000900703 participates in spermidine biosynthetic process (GO:0008295) 20150313: Bacteria _PTN000168362 participates in spermidine biosynthetic process (GO:0008295) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).