# HISTORY 28 Sep 2016: Saved by mfeuerma using Paint 2.22 # molecular_function 20160928: Eukaryota_PTN000161400 contributes to function cytochrome-c oxidase activity (GO:0004129) 20160928: Eukaryota_PTN000161400 has function enzyme regulator activity (GO:0030234) # cellular_component 20160928: Opisthokonta_PTN000161401 is found in mitochondrial respiratory chain complex IV (GO:0005751) # biological_process 20160928: Eukaryota_PTN000161400 participates in generation of precursor metabolites and energy (GO:0006091) 20160928: Eukaryota_PTN000161400 participates in mitochondrial electron transport, cytochrome c to oxygen (GO:0006123) 20160928: Eukaryota_PTN000161400 participates in aerobic respiration (GO:0009060) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).