# HISTORY
07 May 2016: Updated by: TOUCHUP-v1.18
14 Mar 2016: Updated by: TOUCHUP-v1.14
24 Mar 2016: Updated by: TOUCHUP-v1.15

# molecular_function
20150306: node_PTN000159906 has function diaminopimelate decarboxylase activity (GO:0008836) 
20150306: node_PTN000159940 has function arginine decarboxylase activity (GO:0008792) 
20150219: node_PTN000159726 has function ornithine decarboxylase activity (GO:0004586) 
20150306: Euteleostomi_PTN000159733 has function ornithine decarboxylase activator activity (GO:0042978) 
20150306: Amniota_PTN000159772 has function ornithine decarboxylase activator activity (GO:0042978) 
20150306: Mammalia_PTN000159774 has LOST/MODIFIED function ornithine decarboxylase activator activity (GO:0042978) 
20150219: Chromadorea_PTN001352823 has LOST/MODIFIED function ornithine decarboxylase activity (GO:0004586) 
20150219: Euteleostomi_PTN000159733 has LOST/MODIFIED function ornithine decarboxylase activity (GO:0004586) 
20150219: Amniota_PTN000159772 has LOST/MODIFIED function ornithine decarboxylase activity (GO:0004586) 

# cellular_component
20150306: node_PTN000159726 is found in cytoplasm (GO:0005737) 
20150306: Chromadorea_PTN001352823 is NOT found in cytoplasm (GO:0005737) 

# biological_process
20150306: node_PTN000159940 participates in putrescine biosynthetic process from arginine (GO:0033388) 
20150306: node_PTN000159726 participates in putrescine biosynthetic process from ornithine (GO:0033387) 
20150306: Chromadorea_PTN001352823 does NOT participate in putrescine biosynthetic process from ornithine (GO:0033387) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES
MF annotation: "Important residues for ODC activity such as Lys-69, Asp-88, and Cys-360" - pmid:16916800 - was the basis for the propagation in the ornithine decarboxylase node (PTN000159726).  PTN001352823 lacks key residues - annotations were not propagated to this clade.
BP annotation: Both PTN000159940 and PTN000159726 were annotated to putrescine biosynth, the first from arginine, the second from ornithine.  The 2 antizyne inhibitor nodes, PTN000159733 and PTN000159772, were annotated to positive regulation of catalytic activity.

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).