# HISTORY 24 Mar 2016: Updated by: TOUCHUP-v1.15 14 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20150818: root_PTN001352635 has function G-protein coupled receptor binding (GO:0001664) 20150818: root_PTN001352635 has function enzyme activator activity (GO:0008047) # cellular_component 20150818: root_PTN001352635 is found in cytoplasm (GO:0005737) 20150818: Euteleostomi_PTN000159337 is found in extracellular space (GO:0005615) 20150818: Tetrapoda_PTN000896143 is found in multivesicular body (GO:0005771) 20150818: Tetrapoda_PTN000896143 is found in alveolar lamellar body (GO:0097208) # biological_process 20150818: Tetrapoda_PTN000896143 participates in organ morphogenesis (GO:0009887) 20150818: Tetrapoda_PTN000159338 participates in regulation of lipid metabolic process (GO:0019216) 20150818: Tetrapoda_PTN000159338 participates in adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway (GO:0007193) 20150818: Tetrapoda_PTN000159338 participates in prostate gland growth (GO:0060736) 20150818: Tetrapoda_PTN000159338 participates in glycosphingolipid metabolic process (GO:0006687) 20150818: Tetrapoda_PTN000159338 participates in epithelial cell differentiation involved in prostate gland development (GO:0060742) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).