# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 14 Mar 2016: Updated by: TOUCHUP-v1.14 24 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20151112: root_PTN000154975 has function RNA binding (GO:0003723) 20151112: root_PTN000154975 has function ligase activity, forming aminoacyl-tRNA and related compounds (GO:0016876) 20151112: node_PTN000155236 has function proline-tRNA ligase activity (GO:0004827) 20151112: node_PTN000155083 has function threonine-tRNA ligase activity (GO:0004829) 20151112: node_PTN001688767 has function threonine-tRNA ligase activity (GO:0004829) 20151112: node_PTN000012556 has function glutamine-tRNA ligase activity (GO:0004819) 20151112: Eukaryota_PTN000012559 has function glutamate-tRNA ligase activity (GO:0004818) 20151112: Eukaryota_PTN001688809 has function glutamate-tRNA ligase activity (GO:0004818) 20151112: node_PTN000012469 has function glutamate-tRNA ligase activity (GO:0004818) 20151112: node_PTN000154976 has function proline-tRNA ligase activity (GO:0004827) 20151112: Bilateria_PTN000154981 has LOST/MODIFIED function proline-tRNA ligase activity (GO:0004827) # cellular_component 20151112: Eukaryota_PTN000155239 is found in cytoplasm (GO:0005737) 20151112: Embryophyta_PTN000894131 is found in mitochondrion (GO:0005739) 20151112: Embryophyta_PTN000894131 is found in chloroplast stroma (GO:0009570) 20151112: node_PTN000155083 is found in cytoplasm (GO:0005737) 20151112: Saccharomycetales_PTN000894001 is found in mitochondrion (GO:0005739) 20151112: Amniota_PTN001688712 is found in mitochondrion (GO:0005739) 20151112: Eukaryota_PTN001351302 is found in mitochondrion (GO:0005739) 20151112: Eukaryota_PTN001351302 is found in chloroplast stroma (GO:0009570) 20151112: node_PTN001688767 is found in cytosol (GO:0005829) 20151112: node_PTN000012556 is found in cytosol (GO:0005829) 20151112: node_PTN000012558 is found in mitochondrion (GO:0005739) 20151112: cellular organisms_PTN001688851 is found in mitochondrion (GO:0005739) 20151112: Viridiplantae_PTN000012532 is found in chloroplast stroma (GO:0009570) 20151112: node_PTN000804412 is found in cytosol (GO:0005829) 20151112: Eukaryota_PTN000154977 is found in mitochondrion (GO:0005739) 20151112: Bacteria _PTN000155068 is found in cytosol (GO:0005829) 20151112: Archaea_PTN000012689 is NOT found in mitochondrion (GO:0005739) # biological_process 20151112: root_PTN000154975 participates in tRNA aminoacylation for protein translation (GO:0006418) 20151112: node_PTN000155236 participates in prolyl-tRNA aminoacylation (GO:0006433) 20151112: node_PTN000155083 participates in threonyl-tRNA aminoacylation (GO:0006435) 20151112: Saccharomycetales_PTN000894001 participates in mitochondrial threonyl-tRNA aminoacylation (GO:0070159) 20151112: Amniota_PTN001688712 participates in mitochondrial threonyl-tRNA aminoacylation (GO:0070159) 20151112: node_PTN000012556 participates in glutaminyl-tRNA aminoacylation (GO:0006425) 20151112: Eukaryota_PTN000012559 participates in glutamyl-tRNA aminoacylation (GO:0006424) 20151112: Eukaryota_PTN001688809 participates in glutamyl-tRNA aminoacylation (GO:0006424) 20151112: node_PTN000012469 participates in glutamyl-tRNA aminoacylation (GO:0006424) 20151112: cellular organisms_PTN001688851 participates in tRNA aminoacylation for mitochondrial protein translation (GO:0070127) 20151112: node_PTN000154976 participates in prolyl-tRNA aminoacylation (GO:0006433) 20151112: Bilateria_PTN000154981 participates in mitochondrial genome maintenance (GO:0000002) 20151112: Archaea_PTN000012689 does NOT participate in tRNA aminoacylation for mitochondrial protein translation (GO:0070127) 20151112: Bilateria_PTN000154981 does NOT participate in prolyl-tRNA aminoacylation (GO:0006433) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED ## Annotations that have been removed. 20151112: Saccharomycetales_PTN000893961 to cytoplasmic translation (GO:0002181) using [SGD:S000001340] - lacks supporting evidence # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).