# HISTORY 24 Mar 2016: Updated by: TOUCHUP-v1.15 14 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20140210: Euteleostomi_PTN000152007 has function hormone activity (GO:0005179) 20140210: Euteleostomi_PTN000152007 has function glucagon receptor binding (GO:0031769) # cellular_component 20140210: Euteleostomi_PTN000152007 is found in extracellular space (GO:0005615) # biological_process 20140210: Euteleostomi_PTN000152007 participates in adenylate cyclase-modulating G-protein coupled receptor signaling pathway (GO:0007188) 20140210: Euteleostomi_PTN000152007 participates in negative regulation of apoptotic process (GO:0043066) 20140210: Euteleostomi_PTN000152007 participates in protein kinase A signaling (GO:0010737) 20140210: Euteleostomi_PTN000152007 participates in positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:0035774) 20140210: Euteleostomi_PTN000152007 participates in response to starvation (GO:0042594) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES family is missing many important primary annotations, for example positive regulation of gluconeogenesis. # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).