# HISTORY 31 Aug 2016: Saved by pascalegaudet using Paint 2.22 # molecular_function 20160829: Eukaryota_PTN000151466 has function cysteine-type endopeptidase inhibitor activity (GO:0004869) 20160831: Eukaryota_PTN000151466 has function protease binding (GO:0002020) # cellular_component 20160831: Euarchontoglires_PTN000151609 is found in extracellular space (GO:0005615) 20160831: Eumetazoa_PTN000892621 is found in extracellular space (GO:0005615) # biological_process 20160831: Eukaryota_PTN000151466 participates in negative regulation of cysteine-type endopeptidase activity (GO:2000117) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).