# HISTORY 15 Aug 2016: Saved by pascalegaudet using Paint 2.22 # molecular_function 20160811: Amniota_PTN001348163 has function histone binding (GO:0042393) 20160811: Euteleostomi_PTN000146902 has function phosphatase inhibitor activity (GO:0019212) 20160811: Eukaryota_PTN000146830 has function histone binding (GO:0042393) # cellular_component 20160811: Eukaryota_PTN000146830 is found in nucleus (GO:0005634) # biological_process 20160811: Amniota_PTN001348163 participates in nucleosome assembly (GO:0006334) 20160811: Eukaryota_PTN000146830 participates in histone exchange (GO:0043486) 20160811: Eukaryota_PTN000146830 participates in nucleosome assembly (GO:0006334) 20160815: Amniota_PTN001348163 participates in regulation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0043281) 20160815: Eukaryota_PTN000146830 participates in nucleocytoplasmic transport (GO:0006913) 20160811: Tetrapoda_PTN000146837 does NOT participate in histone exchange (GO:0043486) 20160811: Tetrapoda_PTN000146837 does NOT participate in nucleosome assembly (GO:0006334) 20160815: Dictyostelium_PTN001684940 does NOT participate in regulation of apoptotic process (GO:0042981) 20160815: Alveolata_PTN001348173 does NOT participate in regulation of apoptotic process (GO:0042981) 20160815: Excavarus_PTN000890073 does NOT participate in regulation of apoptotic process (GO:0042981) 20160815: Viridiplantae_PTN000146949 does NOT participate in regulation of apoptotic process (GO:0042981) 20160815: Eukaryota_PTN000146830 participates in regulation of apoptotic process (GO:0042981) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES Recent review: PMID:25156960 # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).