# HISTORY 24 Mar 2016: Updated by: TOUCHUP-v1.15 14 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20140916: cellular organisms_PTN000143422 has function DNA polymerase processivity factor activity (GO:0030337) # cellular_component 20140919: cellular organisms_PTN000143422 is found in PCNA complex (GO:0043626) 20140512: Eukaryota_PTN000143427 is found in nucleus (GO:0005634) # biological_process 20140919: cellular organisms_PTN000143422 participates in leading strand elongation (GO:0006272) 20140919: Eukaryota_PTN000143427 participates in translesion synthesis (GO:0019985) 20140512: Eukaryota_PTN000143427 participates in mismatch repair (GO:0006298) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES Annotated by RB PG 2014-09-19 Propagated DNA polymerase processivity factor activity (GO:0030337) to root, since bacterial PCNA can also mediate this role. # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).