# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 14 Mar 2016: Updated by: TOUCHUP-v1.14 24 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20140815: root_PTN000136006 has function GTPase activity (GO:0003924) # cellular_component 20140815: root_PTN000136006 is found in lysosome (GO:0005764) 20140815: root_PTN000136006 is found in EGO complex (GO:0034448) 20140815: root_PTN000136006 is found in nucleus (GO:0005634) 20140815: root_PTN000136006 is found in Gtr1-Gtr2 GTPase complex (GO:1990131) # biological_process 20140815: root_PTN000136006 participates in cellular response to amino acid stimulus (GO:0071230) 20140815: root_PTN000136006 participates in regulation of autophagy (GO:0010506) 20140815: root_PTN000136006 participates in cellular response to starvation (GO:0009267) 20140815: root_PTN000136006 participates in positive regulation of TOR signaling (GO:0032008) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).