# HISTORY
24 Mar 2016: Updated by: TOUCHUP-v1.15
14 Mar 2016: Updated by: TOUCHUP-v1.14

# molecular_function
20150305: root_PTN000129453 has function ribonuclease III activity (GO:0004525) 
20150305: root_PTN000129453 has function double-stranded RNA binding (GO:0003725) 

# cellular_component
20150305: Eukaryota_PTN000129454 is found in nucleus (GO:0005634) 

# biological_process
20150305: root_PTN000129453 participates in RNA processing (GO:0006396) 
20150305: root_PTN000129453 participates in RNA phosphodiester bond hydrolysis, endonucleolytic (GO:0090502) 
20150305: Eukaryota_PTN000129454 participates in production of siRNA involved in RNA interference (GO:0030422) 
20150305: Eukaryota_PTN000129454 participates in primary miRNA processing (GO:0031053) 
20150305: Eukaryota_PTN000129454 participates in pre-miRNA processing (GO:0031054) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES
This family belongs to DROSHA class of the Ribonuclease III.
5-March-2015, HM

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).