# HISTORY 24 Mar 2016: Updated by: TOUCHUP-v1.15 14 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20150709: root_PTN000129048 has function drug transmembrane transporter activity (GO:0015238) 20150709: Mammalia_PTN000129178 has function monovalent cation:proton antiporter activity (GO:0005451) 20150709: Magnoliophyta_PTN000129324 has function solute:proton antiporter activity (GO:0015299) 20150709: Bacteria _PTN000129414 has function antibiotic transporter activity (GO:0042895) 20150709: Pentapetalae_PTN001676627 has function citrate transmembrane transporter activity (GO:0015137) 20150709: Bacteria _PTN001341949 has function lipid-linked peptidoglycan transporter activity (GO:0015648) 20150709: Bacteria _PTN001341949 has LOST/MODIFIED function drug transmembrane transporter activity (GO:0015238) # cellular_component 20150709: Mammalia_PTN000129178 is found in membrane-bounded vesicle (GO:0031988) 20150709: Magnoliophyta_PTN000129366 is found in plasma membrane (GO:0005886) 20150709: Magnoliophyta_PTN001341902 is found in Golgi transport complex (GO:0017119) 20150709: Magnoliophyta_PTN000129324 is found in vacuolar membrane (GO:0005774) 20150709: node_PTN001676495 is found in plasma membrane (GO:0005886) 20150709: Pentapetalae_PTN001676627 is found in plasma membrane (GO:0005886) 20150709: Bacteria _PTN000744762 is found in plasma membrane (GO:0005886) 20150709: Bacteria _PTN001341949 is found in integral component of plasma membrane (GO:0005887) # biological_process 20150709: root_PTN000129048 participates in drug transmembrane transport (GO:0006855) 20150709: Mammalia_PTN000129178 participates in organic cation transport (GO:0015695) 20150709: Magnoliophyta_PTN000129366 participates in regulation of stomatal opening (GO:1902456) 20150709: Bacteria _PTN000129414 participates in antibiotic transport (GO:0042891) 20150709: Bacteria _PTN000129414 participates in response to antibiotic (GO:0046677) 20150709: Bacteria _PTN001341949 participates in lipid translocation (GO:0034204) 20150709: Bacteria _PTN001341949 participates in peptidoglycan biosynthetic process (GO:0009252) 20150709: Bacteria _PTN001341949 does NOT participate in drug transmembrane transport (GO:0006855) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).