# HISTORY
24 Mar 2016: Updated by: TOUCHUP-v1.15
21 Mar 2016: Updated by: TOUCHUP-v1.14

# molecular_function

# cellular_component

# biological_process

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES
Phylogeny
The main clades, with somewhat strange species distribution. There is very little experimental data, so it doesn't matter because no propagation would be made to AN0.
MF
Human is annotated to vinculin binding by IP. Can this be propagated?
CC
No CC annotation.
BP
Worm has two annotations to growth and development processes. Do not propagate.

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).