# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 14 Mar 2016: Updated by: TOUCHUP-v1.14 24 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20150819: cellular organisms_PTN000120503 has function AU-rich element binding (GO:0017091) # cellular_component 20150819: cellular organisms_PTN000120503 is found in cytoplasmic exosome (RNase complex) (GO:0000177) 20150819: cellular organisms_PTN000120503 is found in nuclear exosome (RNase complex) (GO:0000176) 20150819: Archaea_PTN000120692 is NOT found in nuclear exosome (RNase complex) (GO:0000176) # biological_process 20150819: cellular organisms_PTN000120503 participates in rRNA catabolic process (GO:0016075) 20150819: node_PTN000120504 participates in exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay (GO:0043928) 20150819: node_PTN000120504 participates in nuclear polyadenylation-dependent tRNA catabolic process (GO:0071038) 20150819: node_PTN000120504 participates in nuclear polyadenylation-dependent mRNA catabolic process (GO:0071042) 20150819: node_PTN000120504 participates in nuclear polyadenylation-dependent rRNA catabolic process (GO:0071035) 20150819: node_PTN000120504 participates in exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (GO:0000467) 20150819: node_PTN000120504 participates in nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' (GO:0034427) 20150819: node_PTN000120504 participates in U1 snRNA 3'-end processing (GO:0034473) 20150819: node_PTN000120504 participates in U4 snRNA 3'-end processing (GO:0034475) 20150819: node_PTN000120504 participates in U5 snRNA 3'-end processing (GO:0034476) 20150819: node_PTN000120504 participates in nuclear mRNA surveillance (GO:0071028) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES MAF: Non-catalytic compononents of exosome. # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).