# HISTORY 24 Mar 2016: Updated by: TOUCHUP-v1.15 14 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20150722: root_PTN000118214 contributes to function deaminase activity (GO:0019239) 20150722: Eukaryota_PTN000118391 has function tRNA-specific adenosine-34 deaminase activity (GO:0052717) 20150722: Saccharomycetaceae_PTN000118339 has function 5-amino-6-(5-phosphoribosylamino)uracil reductase activity (GO:0008703) 20150722: Eukaryota_PTN001669009 has function tRNA-specific adenosine deaminase activity (GO:0008251) 20150722: Embryophyta_PTN000871439 has function guanosine deaminase activity (GO:0047974) 20150722: node_PTN001311753 has function pseudouridine synthase activity (GO:0009982) 20150722: node_PTN001669236 has function pseudouridine synthase activity (GO:0009982) 20150722: node_PTN000824384 has function pseudouridine synthase activity (GO:0009982) 20150722: Bacteria _PTN000118315 has function diaminohydroxyphosphoribosylaminopyrimidine deaminase activity (GO:0008835) 20150722: Bacteria _PTN000118315 has function 5-amino-6-(5-phosphoribosylamino)uracil reductase activity (GO:0008703) # cellular_component 20150722: Eukaryota_PTN000118391 is found in tRNA-specific adenosine-34 deaminase complex (GO:0052718) 20150722: Viridiplantae_PTN000118273 is found in chloroplast (GO:0009507) 20150722: Eukaryota_PTN000118217 is found in cytosol (GO:0005829) 20150722: node_PTN000046872 is found in cytosol (GO:0005829) 20150722: node_PTN000046795 is found in mitochondrion (GO:0005739) 20150722: Eukaryota_PTN001669268 is found in tRNA-specific adenosine-34 deaminase complex (GO:0052718) 20150722: Bacteria _PTN000046848 is found in cytosol (GO:0005829) 20150722: Bacteria _PTN000118315 is found in cytosol (GO:0005829) # biological_process 20150722: root_PTN000118214 participates in RNA modification (GO:0009451) 20150722: Eukaryota_PTN000118391 participates in tRNA modification (GO:0006400) 20150722: Eukaryota_PTN001669009 participates in tRNA wobble adenosine to inosine editing (GO:0002100) 20150722: Bacteria _PTN000118285 participates in tRNA wobble adenosine to inosine editing (GO:0002100) 20150722: node_PTN001311753 participates in enzyme-directed rRNA pseudouridine synthesis (GO:0000455) 20150722: node_PTN001669236 participates in tRNA pseudouridine synthesis (GO:0031119) 20150722: node_PTN001669236 participates in enzyme-directed rRNA pseudouridine synthesis (GO:0000455) 20150722: node_PTN001669263 participates in pyrimidine-containing compound salvage (GO:0008655) 20150722: node_PTN001669263 participates in cytidine metabolic process (GO:0046087) 20150722: node_PTN001669263 participates in cytosine metabolic process (GO:0019858) 20150722: node_PTN000824384 participates in tRNA pseudouridine synthesis (GO:0031119) 20150722: Bacteria _PTN000118315 participates in riboflavin biosynthetic process (GO:0009231) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).