# HISTORY 24 Mar 2016: Updated by: TOUCHUP-v1.15 14 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20150528: root_PTN000117595 has function ribosome binding (GO:0043022) 20150528: root_PTN000117595 has function translation release factor activity, codon specific (GO:0016149) 20150528: node_PTN000117866 has function translation release factor activity, codon nonspecific (GO:0016150) 20150528: node_PTN000117866 has function aminoacyl-tRNA hydrolase activity (GO:0004045) 20150528: node_PTN000117866 has LOST/MODIFIED function translation release factor activity, codon specific (GO:0016149) # cellular_component 20150528: node_PTN000744605 is found in mitochondrial large ribosomal subunit (GO:0005762) 20150528: Eukaryota_PTN000117641 is found in mitochondrion (GO:0005739) # biological_process 20150528: node_PTN000117866 participates in rescue of stalled ribosome (GO:0072344) 20150528: node_PTN000744605 participates in mitochondrial translational termination (GO:0070126) 20150528: Eukaryota_PTN000117641 participates in mitochondrial translational termination (GO:0070126) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).