# HISTORY
07 May 2016: Updated by: TOUCHUP-v1.18
14 Mar 2016: Updated by: TOUCHUP-v1.14
24 Mar 2016: Updated by: TOUCHUP-v1.15

# molecular_function
20150211: Eukaryota_PTN000108561 has function potassium ion leak channel activity (GO:0022841) 
20150211: Euteleostomi_PTN000108904 has function outward rectifier potassium channel activity (GO:0015271) 

# cellular_component
20150211: Eukaryota_PTN000108561 is found in integral component of plasma membrane (GO:0005887) 
20150211: node_PTN000109155 is found in plant-type vacuole membrane (GO:0009705) 

# biological_process
20150211: Eukaryota_PTN000108561 participates in stabilization of membrane potential (GO:0030322) 
20150211: Eukaryota_PTN000108561 participates in potassium ion transmembrane transport (GO:0071805) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES
The main function of this family of protein is to maintain resting membrane potential.
The best review paper about this family is PubMed: 20393194 (http://physrev.physiology.org/content/90/2/559.long).
Some members gain the function as a rectifying channel (either inward or outward). The voltage dependency is also gained for some members.
Feb. 11, 2015, HM

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).