# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 14 Mar 2016: Updated by: TOUCHUP-v1.14 24 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20150710: root_PTN000105988 has function hydrolase activity (GO:0016787) 20150710: Opisthokonta_PTN001659992 has function haloalkane dehalogenase activity (GO:0018786) 20150710: Bacteria _PTN000106947 has function thiolester hydrolase activity (GO:0016790) 20150710: rosids_PTN001660489 has function epoxide hydrolase activity (GO:0004301) 20150710: Bacteria _PTN000107313 has function lipase activity (GO:0016298) 20150710: Eukaryota_PTN001660620 has function serine O-acetyltransferase activity (GO:0009001) 20150710: Viridiplantae_PTN001661043 has function pheophytinase activity (GO:0080124) 20150710: node_PTN000107240 has function epoxide hydrolase activity (GO:0004301) 20150710: Eukaryota_PTN000105999 has function carboxylic ester hydrolase activity (GO:0052689) 20150710: Euteleostomi_PTN000106029 has function lysophosphatidic acid acyltransferase activity (GO:0042171) 20150710: Euteleostomi_PTN000106556 has function acylglycerol lipase activity (GO:0047372) 20150710: Euteleostomi_PTN000106556 has function phospholipase activity (GO:0004620) 20150710: Gammaproteobacteria_PTN001661445 has function 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity (GO:0070205) # cellular_component 20150710: Bacteria _PTN000106947 is found in cytosol (GO:0005829) 20150710: rosids_PTN001660489 is found in cytosol (GO:0005829) 20150710: Chordata_PTN000862681 is found in mitochondrion (GO:0005739) 20150710: Viridiplantae_PTN001661043 is found in chloroplast (GO:0009507) 20150710: Embryophyta_PTN001661068 is found in endoplasmic reticulum (GO:0005783) 20150710: Embryophyta_PTN001661068 is found in vacuolar membrane (GO:0005774) 20150710: Embryophyta_PTN001661068 is found in mitochondrion (GO:0005739) 20150710: Bilateria_PTN000106002 is found in lipid particle (GO:0005811) 20150710: Euteleostomi_PTN000106029 is found in cytoplasm (GO:0005737) 20150710: Bilateria_PTN000106991 is found in cytoplasm (GO:0005737) 20150710: Euteleostomi_PTN000106556 is found in mitochondrion (GO:0005739) 20150710: Gammaproteobacteria_PTN001661445 is found in cytosol (GO:0005829) # biological_process 20150710: Opisthokonta_PTN001659992 participates in halogenated hydrocarbon catabolic process (GO:0042206) 20150710: Metazoa_PTN001660296 participates in cellular amino acid metabolic process (GO:0006520) 20150710: Magnoliophyta_PTN000107081 participates in secondary shoot formation (GO:0010223) 20150710: Magnoliophyta_PTN000107081 participates in strigolactone biosynthetic process (GO:1901601) 20150710: Bacteria _PTN000107313 participates in fatty acid catabolic process (GO:0009062) 20150710: Eukaryota_PTN001660620 participates in cysteine biosynthetic process (GO:0019344) 20150710: Metazoa_PTN001660979 participates in regulation of lipid storage (GO:0010883) 20150710: Metazoa_PTN001660979 participates in mesoderm development (GO:0007498) 20150710: Viridiplantae_PTN001661043 participates in chlorophyll catabolic process (GO:0015996) 20150710: Embryophyta_PTN001661068 participates in auxin polar transport (GO:0009926) 20150710: Bilateria_PTN000106002 participates in lipid storage (GO:0019915) 20150710: Bilateria_PTN000106002 participates in lipid metabolic process (GO:0006629) 20150710: Euteleostomi_PTN000106029 participates in phosphatidic acid biosynthetic process (GO:0006654) 20150710: Euteleostomi_PTN000106029 participates in positive regulation of triglyceride catabolic process (GO:0010898) 20150710: Euteleostomi_PTN000106556 participates in acylglycerol catabolic process (GO:0046464) 20150710: Gammaproteobacteria_PTN001661445 participates in menaquinone biosynthetic process (GO:0009234) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).