# HISTORY 24 Mar 2016: Updated by: TOUCHUP-v1.15 14 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20141107: Eukaryota_PTN000100519 has function microtubule binding (GO:0008017) # cellular_component 20141107: Eukaryota_PTN000100519 is found in kinetochore (GO:0000776) 20141107: Eukaryota_PTN000100519 is found in kinesin complex (GO:0005871) 20141107: Eukaryota_PTN000100519 is found in centrosome (GO:0005813) 20141107: Dikarya_PTN000858805 is NOT found in centrosome (GO:0005813) # biological_process 20141107: Eukaryota_PTN000100519 participates in chromosome segregation (GO:0007059) 20141107: Eukaryota_PTN000100519 participates in cell migration (GO:0016477) 20141107: Eukaryota_PTN000100519 participates in microtubule nucleation (GO:0007020) 20141107: Eukaryota_PTN000100519 participates in establishment of mitotic spindle orientation (GO:0000132) 20141107: Eukaryota_PTN000100519 participates in centrosome localization (GO:0051642) 20141107: Eukaryota_PTN000100519 participates in vesicle transport along microtubule (GO:0047496) 20141107: Eukaryota_PTN000100519 participates in establishment of chromosome localization (GO:0051303) 20141107: Eukaryota_PTN000100519 participates in mitotic centrosome separation (GO:0007100) 20141107: Euteleostomi_PTN000100553 participates in regulation of neuron projection development (GO:0010975) 20141107: Dikarya_PTN000858805 does NOT participate in centrosome localization (GO:0051642) 20141107: Dikarya_PTN000858805 does NOT participate in mitotic centrosome separation (GO:0007100) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).