# HISTORY 24 Mar 2016: Updated by: TOUCHUP-v1.15 14 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20140829: Opisthokonta_PTN000096563 has function tropomyosin binding (GO:0005523) # cellular_component 20140829: Opisthokonta_PTN000096563 is found in cytoskeleton (GO:0005856) 20140829: Bilateria_PTN000096564 is found in myofibril (GO:0030016) 20140829: node_PTN000096567 is found in striated muscle thin filament (GO:0005865) # biological_process 20140829: Opisthokonta_PTN000096563 participates in actin filament organization (GO:0007015) 20140829: Bilateria_PTN000096564 participates in myofibril assembly (GO:0030239) 20140829: node_PTN000096567 participates in muscle contraction (GO:0006936) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).