# HISTORY
24 Mar 2016: Updated by: TOUCHUP-v1.15
14 Mar 2016: Updated by: TOUCHUP-v1.14

# molecular_function
20150217: cellular organisms_PTN000096022 has function snoRNA binding (GO:0030515) 

# cellular_component
20141113: cellular organisms_PTN000096022 is found in box C/D snoRNP complex (GO:0031428) 
20150217: cellular organisms_PTN000096022 is found in small-subunit processome (GO:0032040) 
20141113: Archaea_PTN000096166 is NOT found in box C/D snoRNP complex (GO:0031428) 
20150217: Archaea_PTN000096166 is NOT found in small-subunit processome (GO:0032040) 

# biological_process
20141113: cellular organisms_PTN000096022 participates in rRNA modification (GO:0000154) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES
This family contains the NOP56 and NOP58 proteins which are protein subunits of box C/D snoRNP complexes.
The majority of the box C/D snoRNP complexes function as methylation guides to target methylation to specific ribose moities of nucleotides, most often within the 18S or 25S rRNAs, but also within other RNA substrates. Some box C/D snoRNPs, e.g. U3, U8, U14, and U22 are involved in cleavages of the pre-rRNA transcript to separate the SSU rRNA from the remainder of the rRNA transcript, but are not implicated as methylation guides (PMID:9159079, PMID:10690410). Many of the box C/D snoRNAs, including those like U3 and those with methylation guide activity are found within large complexes such as the 90S pre-ribosome and the Small SubUnit (SSU) processome which are invovled in the initial cleavages of the rRNA transcript and further maturation of the SSU (PMID:17515605, PMID:15590835).

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).