# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 14 Mar 2016: Updated by: TOUCHUP-v1.14 24 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function # cellular_component 20150619: Eukaryota_PTN000093963 is found in histone acetyltransferase complex (GO:0000123) 20150619: Eukaryota_PTN000093964 is found in NuA4 histone acetyltransferase complex (GO:0035267) # biological_process 20150619: Eukaryota_PTN000093963 participates in histone acetylation (GO:0016573) 20150619: Eukaryota_PTN000093963 participates in chromatin remodeling (GO:0006338) 20150619: Eukaryota_PTN000093964 participates in histone deacetylation (GO:0016575) 20150619: Eukaryota_PTN000093964 participates in chromatin silencing (GO:0006342) 20150619: Eukaryota_PTN000093964 participates in histone H2A acetylation (GO:0043968) 20150619: Eukaryota_PTN000093964 participates in histone H4 acetylation (GO:0043967) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES Dispute SGD Q12432 EAF3 GO:0004402 histone acetyltransferase activity IDA PMID:11036083 # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).